/* BA1's public editorial layer. Other consultation editions do not load this file. */
.patient-essentials{padding-top:66px;padding-bottom:36px}
.essentials-heading{display:flex;align-items:start;justify-content:space-between;gap:30px;margin-bottom:36px}
.essentials-heading h2{font-size:48px;margin:0;min-width:49%}
.essentials-heading .eyebrow{padding-top:10px}
.essentials-grid{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:35px}
.essentials-grid article{border-top:2px solid var(--brand-purple);padding:22px 0 6px}
.essential-number{font-size:9px;letter-spacing:1.6px;color:var(--brand-purple);font-weight:600}
.essentials-grid h3{font-size:34px;margin:20px 0 16px}
.essentials-grid p{font-size:13px;color:var(--muted);max-width:360px}
.essentials-grid a{display:inline-block;margin-top:20px;font-size:11px;border-bottom:1px solid var(--line);padding:4px 0}
.page-jumps{display:flex;align-items:center;gap:24px;flex-wrap:wrap;border-top:1px solid var(--line);border-bottom:1px solid var(--line);margin-top:38px;padding:15px 0}
.page-jumps>span{font-size:8px;letter-spacing:1.7px;color:var(--muted);margin-right:auto}
.page-jumps a{font-size:11px;padding:5px 0}
.essentials-next{font-size:12px;color:var(--muted);margin-top:20px}
.essentials-next a{display:inline-block;color:var(--brand-purple);border-bottom:1px solid var(--line);padding:5px 0}
.page-jumps a:hover,.research-jumps a:hover{color:var(--brand-purple);text-decoration:underline;text-underline-offset:5px}
.prf-biology{background:var(--brand-purple);color:var(--paper)}
.prf-biology .eyebrow,.prf-biology .section-heading>p{color:#e2dbea}
.prf-biology h2 em{color:var(--brand-yellow)}
.prf-biology h2{max-width:650px;font-size:clamp(44px,4.2vw,64px)}
.biology-pathway{display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:40px;list-style:none;padding:0;margin:45px 0 35px}
.biology-pathway li{position:relative}
.biology-pathway li:not(:last-child):after{content:'→';position:absolute;right:-27px;top:14px;color:var(--brand-yellow);font-size:25px}
.biology-symbol{width:60px;height:60px;display:grid;place-items:center;border:1px solid #d4e14188;border-radius:50%;font-size:11px;letter-spacing:2px;color:var(--brand-yellow)}
.network-symbol{border-radius:14px;transform:rotate(-5deg);background:repeating-linear-gradient(45deg,transparent,transparent 10px,#d4e1410a 11px,#d4e1410a 12px)}
.biology-pathway h3{font-size:33px;margin:23px 0 16px}
.biology-pathway p{font-size:13px;color:#e2dbea}
.biology-boundary{border-left:3px solid var(--brand-yellow);padding:13px 22px;margin-top:40px;font-size:12px;color:#e2dbea;max-width:950px}
.biology-boundary strong{color:#fff;font-weight:600}
.biology-boundary a{display:inline-block;border-bottom:1px solid #d4e14188;color:var(--brand-yellow);margin-top:5px}
.science-glossary{margin-top:35px;border-top:1px solid #ffffff40;border-bottom:1px solid #ffffff40}
.science-glossary summary{cursor:pointer;padding:22px 4px;font-size:13px}
.science-glossary>div{max-width:900px;padding:0 4px 25px;color:#e2dbea;font-size:12px}
.science-glossary p+p{margin-top:14px}
.science-glossary a{color:var(--brand-yellow);text-decoration:underline;text-underline-offset:4px}
.prf-biology :is(a,summary):focus-visible{outline-color:var(--brand-yellow)}
.research-library{background:#f3f0f6}
.research-context{display:grid;grid-template-columns:1fr 1fr;gap:36px;padding:24px 28px;background:var(--paper);border-left:3px solid var(--brand-purple);font-size:12px;color:var(--muted)}
.research-context strong{color:var(--ink)}
.research-jumps{display:flex;gap:12px;flex-wrap:wrap;margin:28px 0 50px}
.research-jumps a{display:flex;gap:26px;align-items:center;justify-content:space-between;min-height:46px;padding:10px 20px;border:1px solid var(--line);font-size:12px}
.research-jumps span{color:var(--brand-purple)}
.research-group{display:grid;grid-template-columns:1fr 1.45fr;gap:7%;margin-top:45px;padding-top:42px;border-top:1px solid var(--line);scroll-margin-top:25px}
.research-group-intro h3{font-size:37px;margin:18px 0}
.research-group-intro>p:last-child{color:var(--muted);font-size:12px;max-width:380px}
.study{background:var(--paper);border:1px solid var(--line)}
.study+.study{margin-top:12px}
.study summary{list-style:none;display:flex;align-items:center;justify-content:space-between;gap:22px;padding:22px 25px;cursor:pointer}
.study summary::-webkit-details-marker{display:none}
.study-label{display:block;font-size:9px;color:var(--brand-purple);letter-spacing:1px;margin-bottom:10px;text-transform:uppercase}
.study-title{display:block;font-size:14px;line-height:1.6;font-weight:500}
.study-toggle{font-size:25px;line-height:1;color:var(--brand-purple);flex:none}
.study[open] .study-toggle{font-size:0}
.study[open] .study-toggle:after{content:'−';font-size:25px}
.study[open]{border-color:#9686ad}
.study[open] summary{border-bottom:1px solid var(--line)}
.study-body{padding:24px 25px}
.study-body dl{margin:0;font-size:12px}
.study-body dl>div+div{margin-top:19px}
.study-body dt{font-weight:600;margin-bottom:6px}
.study-body dd{margin:0;color:var(--muted)}
.study-limit{border-left:2px solid var(--brand-purple);padding-left:14px}
.study-body>a{display:inline-block;font-size:11px;border-bottom:1px solid var(--line);margin-top:22px}
.study-citation{font-size:10px;color:var(--muted);margin-top:12px}
.research-bottom-line{background:var(--brand-yellow-light);padding:34px 38px;margin-top:55px}
.research-bottom-line .eyebrow{color:var(--brand-purple)}
.research-bottom-line h3{font-size:38px;margin:18px 0}
.research-bottom-line>p:not(.eyebrow){font-size:13px;max-width:850px}
.research-bottom-line .text-link{margin-top:24px}
.research-review{font-size:10px;color:var(--muted);margin-top:25px;max-width:870px}
.public-footer-links a{border-bottom:1px solid var(--line);padding:5px 0}
.closing .secondary-closing-link{display:table;margin:20px auto 0;font-size:12px;border-bottom:1px solid var(--line)}
@media(max-width:1050px){.essentials-grid{gap:25px}.essentials-grid h3{font-size:31px}.biology-pathway{gap:28px}.biology-pathway li:not(:last-child):after{right:-22px;font-size:20px}.biology-pathway h3{font-size:29px}.research-group{gap:5%;grid-template-columns:1fr 1.5fr}}
@media(max-width:700px){.patient-essentials{padding-top:42px;padding-bottom:20px}.essentials-heading{display:block;margin-bottom:26px}.essentials-heading h2{font-size:42px;margin-top:18px}.essentials-heading h2 br{display:none}.essentials-grid{grid-template-columns:1fr;gap:22px}.essentials-grid article{padding-top:15px}.essentials-grid h3{font-size:32px;margin:14px 0 12px}.essentials-grid h3 br{display:none}.essentials-grid p{max-width:none;font-size:12px}.essentials-grid a{margin-top:10px;min-height:38px;padding-top:8px}.page-jumps{gap:8px 20px;margin-top:26px}.page-jumps>span{width:100%}.page-jumps a{min-height:38px}.biology-pathway{grid-template-columns:1fr;gap:28px;margin-top:30px}.biology-pathway li{padding-left:70px;min-height:60px}.biology-symbol{position:absolute;left:0;top:2px;width:46px;height:46px}.biology-pathway li:not(:last-child):after{content:'';left:22px;top:60px;bottom:-16px;right:auto;width:1px;background:#d4e14166}.biology-pathway h3{font-size:31px;margin:0 0 13px}.biology-pathway p{font-size:12px}.biology-boundary{padding:8px 16px;margin-top:30px}.science-glossary summary{font-size:12px}.research-context{grid-template-columns:1fr;gap:18px;padding:22px}.research-jumps{display:grid;grid-template-columns:1fr 1fr;gap:10px;margin-bottom:30px}.research-group{grid-template-columns:1fr;gap:24px;margin-top:30px;padding-top:30px}.research-group-intro h3{font-size:34px}.research-group-intro>p:last-child{max-width:none}.study summary{padding:20px;gap:14px}.study-title{font-size:13px}.study-label{font-size:8px;line-height:1.8}.study-body{padding:20px}.research-bottom-line{padding:27px 23px;margin-top:35px}.research-bottom-line h3{font-size:34px}.research-bottom-line>p:not(.eyebrow){font-size:12px}.public-footer-links{justify-content:start;gap:12px 22px}}
@media print{.patient-essentials,.prf-biology,.research-library{display:none!important}}